Semi-global stabilization and output regulation of linear systems subject to state and/or input constraints have been studied in our earlier work by using state feedback. For the same problems, observer based measurement feedback control designs are the topics of this paper. High-gain observers are used in the feedback design in order to obtain accurate estimates of the state so that the constraint violation can be avoided. Due to the peaking phenomenon associated with a high-gain observer, a special saturation protection is built in the control laws to avoid possible constraint violation. The results in this paper show that the semi-global stabilization and semi-global output regulation problems for constrained linear systems are solvable via measurement feedback under solvability conditions similar to those in the state feedback.