Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 16646-16650 |
| Number of pages | 5 |
| Journal | Chemistry : A European Journal |
| Volume | 19 |
| Issue number | 49 |
| DOIs | |
| Publication status | Published - 2013 |
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Self-assembled fluorescent organic nanoparticles for live cell imaging. / Fischer, I.; Petkau, K.; Dorland, Y.L.; Schenning, A.P.H.J.; Brunsveld, L.
In: Chemistry : A European Journal, Vol. 19, No. 49, 2013, p. 16646-16650.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Self-assembled fluorescent organic nanoparticles for live cell imaging
AU - Fischer, I.
AU - Petkau, K.
AU - Dorland, Y.L.
AU - Schenning, A.P.H.J.
AU - Brunsveld, L.
PY - 2013
Y1 - 2013
N2 - Fluorescent, cell-permeable, organic nanoparticles based on self-assembled p-conjugated oligomers with high absorption cross-sections and high quantum yields have been developed. The nanoparticles are generated with a tuneable density of amino groups for charge-mediated cellular uptake by a straightforward self-assembly protocol, which allows for control over size and toxicity. The results show that a single amino group per ten oligomers is sufficient to achieve cellular uptake. The non-toxic nanoparticles are suitable for both one- and two-photon cellular imaging and flow cytometry, and undergo very efficient cellular uptake.
AB - Fluorescent, cell-permeable, organic nanoparticles based on self-assembled p-conjugated oligomers with high absorption cross-sections and high quantum yields have been developed. The nanoparticles are generated with a tuneable density of amino groups for charge-mediated cellular uptake by a straightforward self-assembly protocol, which allows for control over size and toxicity. The results show that a single amino group per ten oligomers is sufficient to achieve cellular uptake. The non-toxic nanoparticles are suitable for both one- and two-photon cellular imaging and flow cytometry, and undergo very efficient cellular uptake.
U2 - 10.1002/chem.201302647
DO - 10.1002/chem.201302647
M3 - Article
C2 - 24281811
VL - 19
SP - 16646
EP - 16650
JO - Chemistry : A European Journal
JF - Chemistry : A European Journal
SN - 0947-6539
IS - 49
ER -