Abstract
Abstract: An innovative nanomechanical strategy for in vivo biomedical applications is reviewed. The strategy is based on the use of complexes of special functionalized magnetic nanoparticles controlled by an external low-frequency nonheating magnetic field as deformation machines. The advantages of the strategy are the possibility of easily achieved nanoscale locality and molecular selectivity of action (at the level of individual macromolecules and macromolecular structures such as liposomes, living cells, cell organelles), multimodality, safety, and a high potential of therapeutic application, in particular, for noninvasive oncotherapy without drugs.
| Original language | English |
|---|---|
| Pages (from-to) | 374-384 |
| Number of pages | 11 |
| Journal | Russian Metallurgy (Metally) |
| Volume | 2019 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Apr 2019 |
| Externally published | Yes |
Bibliographical note
Funding Information:This work was supported by the Russian Science Foundation (project no. 14-13-00731) and the Russian Foundation for Basic Research (projects nos. 17-54-33027, 17-42-680803, 18-29-09154).
Funding
This work was supported by the Russian Science Foundation (project no. 14-13-00731) and the Russian Foundation for Basic Research (projects nos. 17-54-33027, 17-42-680803, 18-29-09154).
Keywords
- deformation
- macromolecules
- magnetic field
- magnetic nanoparticles
- magnetic therapy
- nanomedicine
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