Sample target substrates with reduced spot size for MALDI-TOF mass spectrometry based on patterned self-assembled monolayers

N. Herzer, R. Eckardt, Stephanie Höppener, U.S. Schubert

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
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Abstract

The wetting properties of structured self-assembled monolayers are used to fabricate sample target substrates for MALDI-TOF mass spectrometry. Combining the advantages of a hydrophobic-hydrophilic surface pattern and the possibility of obtaining micrometer patterns allows an increase in the sensitivity of MALDI-TOF mass spectrometry analysis and a reduction in the traceable concentration down to fmol µL-1. This easy, cheap and fast patterning process provides substrates that allow sensitive, high-resolution mass spectrometry of dilute solutions.
Original languageEnglish
Pages (from-to)2777-2781
JournalAdvanced Functional Materials
Volume19
Issue number17
DOIs
Publication statusPublished - 2009

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