Rod-coil diblock polymerization from a bifunctional NMRP initiator

J.R.I. Knoop, G.J.M. Habraken, H. Menzel, C.E. Koning, A. Heise

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic


We have developed a universal synthetic pathway to rod-coil block copolymers. The concept was proven for the synthesis of poly(benzyl-L-glutamate-b-styrene). A dual initiator contg. a primary amine and a nitroxide group was used in a macroinitiation approach, thereby circumventing all polymer analogous reactions. Good control over the mol. wt. in the ring opening polymn. of benzyl-L-glutamate N-carboxyanhydride (NCA) was obtained in DMF at 0C yielding poly(benzyl-L-glutamates) with low polydispersities around 1.1. The almost quant. incorporation of the dual initiator was confirmed by MALDI-ToF anal. Macroinitiation of styrene by nitroxide mediated controlled radical polymn. (NMP) yielded the block copolymer. The block structure was confirmed by mol. wt. increase upon macroinitiation in size exclusion chromatog. (SEC) and retention time comparison with homopolymers using gradient polymer elution chromatog. (GPEC). While mainly diblock copolymers were obtained, small amts. of triblock copolymer due to radical coupling were also detected.
Original languageEnglish
Title of host publicationAbstracts of Papers, 234th ACS National Meeting, August 19-23, 2007, Boston, MA, United States
Place of PublicationWashington, D. C
PublisherAmerican Chemical Society
Publication statusPublished - 2007


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