Retinal vessel delineation using a brain-inspired wavelet transform and random forest

Jiong Zhang, Yuan Chen, Erik Bekkers, Meili Wang, Behdad Dashtbozorg, Bart M.ter Haar Romeny

Research output: Contribution to journalArticleAcademicpeer-review

97 Citations (Scopus)


This paper presents a supervised retinal vessel segmentation by incorporating vessel filtering and wavelet transform features from orientation scores (OSs), and green intensity. Through an anisotropic wavelet-type transform, a 2D image is lifted to a 3D orientation score in the Lie-group domain of positions and orientations R2⋊S1. Elongated structures are disentangled into their corresponding orientation planes and enhanced via multi-orientation vessel filtering. In addition, scale-selective OSs (in the domain of positions, orientations and scales R2⋊S1×R+) are obtained by adding a scale adaptation to the wavelet transform. Features are optimally extracted by taking maximum orientation responses at multiple scales, to represent vessels of changing calibers. Finally, we train a Random Forest classifier for vessel segmentation. Extensive validations show that our method achieves a competitive segmentation, and better vessel preservation with less false detections compared with the state-of-the-art methods.

Original languageEnglish
Pages (from-to)107-123
Number of pages17
JournalPattern Recognition
Publication statusPublished - 1 Sept 2017


  • Orientation score (OS)
  • Random forest
  • Retinal image
  • Vessel segmentation
  • Wavelet transform


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