Real-time clutter reduction in epi-optoacoustic imaging of human volunteers

Michael Jaeger, Kujtim Gashi, Sara Peeters, Gerrit Held, Stefan Preisser, Martin Frenz

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)


Optoacoustic (OA) imaging in combination with diagnostic pulse-echo ultrasound is most flexibly implemented with irradiation optics and acoustic probe integrated in epi-style in a combined probe. Unfortunately, clinical epi-OA imaging depth is typically limited to one centimetre owing to clutter signals that originates from the site of tissue irradiation. In past years we have developed displacement-compensated averaging (DCA) for clutter reduction, based on the clutter decorrelation that occurs when palpating the tissue using the ultrasound probe. This method has now been implemented on a research ultrasound system for real time scanning with freehand guidance of the linear probe. Volunteer results confirm that clutter is significant in clinical OA imaging, and that DCA significantly improves image contrast as compared to conventional averaging. Clutter reduction is therefore a basic requirement for a successful combination of OA imaging with pulse-echo ultrasound.

Original languageEnglish
Title of host publicationMedical Imaging 2014
Subtitle of host publicationUltrasonic Imaging and Tomography
ISBN (Print)9780819498335
Publication statusPublished - 1 Jan 2014
EventSPIE Medical Imaging 2014 - San Diego, United States
Duration: 18 Feb 201420 Feb 2014

Publication series

NameProceedings of SPIE


ConferenceSPIE Medical Imaging 2014
Country/TerritoryUnited States
CitySan Diego


  • clutter reduction
  • contrast improvement
  • diagnostic imaging
  • imaging depth
  • Optoacoustic imaging
  • photoacoustic imaging


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