Programmed cold sample introduction and multidimensional preparative capillary gas chromatography. Part I: introduction, design and operation of a new mass flow controlled multidimensional GC system

A new design of a mass-flow controlled multidimensional switching system for capillary gas chromatography is introduced and discussed. Large sample amounts can be introduced with a required input band width onto the first column. A combination of cold sample introduction and successive high speed programmed heating of the injector liner is used for this purpose. The potential of such an approach for selective and fast high resolution separations with series coupled wide bore, thick film columns is emphasized, and illustrated for various concentrations.