Probing the solvent-assisted nucleation pathway in chemical self-assembly

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Abstract

Hierarchical self-assembly offers a powerful strategy for producing molecular nanostructures. Although widely used, the mechanistic details of self-assembly processes are poorly understood. We spectroscopically monitored a nucleation process in the self-assembly of p-conjugated molecules into helical supramolecular fibrillar structures. The data support a nucleation-growth pathway that gives rise to a remarkably high degree of cooperativity. Furthermore, we characterize a helical transition in the nucleating species before growth. The self-assembly process depends strongly on solvent structure, suggesting that an organized shell of solvent molecules plays an explicit role in rigidifying the aggregates and guiding them toward further assembly into bundles and/or gels.
LanguageEnglish
Pages80-83
Number of pages4
JournalScience
Volume313
Issue number5783
DOIs
StatePublished - 2006

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Self assembly
Nucleation
Molecules
Nanostructures
Gels

Cite this

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title = "Probing the solvent-assisted nucleation pathway in chemical self-assembly",
abstract = "Hierarchical self-assembly offers a powerful strategy for producing molecular nanostructures. Although widely used, the mechanistic details of self-assembly processes are poorly understood. We spectroscopically monitored a nucleation process in the self-assembly of p-conjugated molecules into helical supramolecular fibrillar structures. The data support a nucleation-growth pathway that gives rise to a remarkably high degree of cooperativity. Furthermore, we characterize a helical transition in the nucleating species before growth. The self-assembly process depends strongly on solvent structure, suggesting that an organized shell of solvent molecules plays an explicit role in rigidifying the aggregates and guiding them toward further assembly into bundles and/or gels.",
author = "P. Jonkheijm and {Schoot, van der}, P.P.A.M. and A.P.H.J. Schenning and E.W. Meijer",
year = "2006",
doi = "10.1126/science.1127884",
language = "English",
volume = "313",
pages = "80--83",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science (AAAS)",
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}

Probing the solvent-assisted nucleation pathway in chemical self-assembly. / Jonkheijm, P.; Schoot, van der, P.P.A.M.; Schenning, A.P.H.J.; Meijer, E.W.

In: Science, Vol. 313, No. 5783, 2006, p. 80-83.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Probing the solvent-assisted nucleation pathway in chemical self-assembly

AU - Jonkheijm,P.

AU - Schoot, van der,P.P.A.M.

AU - Schenning,A.P.H.J.

AU - Meijer,E.W.

PY - 2006

Y1 - 2006

N2 - Hierarchical self-assembly offers a powerful strategy for producing molecular nanostructures. Although widely used, the mechanistic details of self-assembly processes are poorly understood. We spectroscopically monitored a nucleation process in the self-assembly of p-conjugated molecules into helical supramolecular fibrillar structures. The data support a nucleation-growth pathway that gives rise to a remarkably high degree of cooperativity. Furthermore, we characterize a helical transition in the nucleating species before growth. The self-assembly process depends strongly on solvent structure, suggesting that an organized shell of solvent molecules plays an explicit role in rigidifying the aggregates and guiding them toward further assembly into bundles and/or gels.

AB - Hierarchical self-assembly offers a powerful strategy for producing molecular nanostructures. Although widely used, the mechanistic details of self-assembly processes are poorly understood. We spectroscopically monitored a nucleation process in the self-assembly of p-conjugated molecules into helical supramolecular fibrillar structures. The data support a nucleation-growth pathway that gives rise to a remarkably high degree of cooperativity. Furthermore, we characterize a helical transition in the nucleating species before growth. The self-assembly process depends strongly on solvent structure, suggesting that an organized shell of solvent molecules plays an explicit role in rigidifying the aggregates and guiding them toward further assembly into bundles and/or gels.

U2 - 10.1126/science.1127884

DO - 10.1126/science.1127884

M3 - Article

VL - 313

SP - 80

EP - 83

JO - Science

T2 - Science

JF - Science

SN - 0036-8075

IS - 5783

ER -