Polymerization reactions occurring during dinitrophenylation of a-, b-, and w-amino acids with Sanger's reagent

D. Heikens; P.H. Hermans; P.F. Velden, van

doi:10.1038/1741187b0

Polymerization reactions occurring during dinitrophenylation of a-, b-, and w-amino acids with Sanger's reagent

D. Heikens, P.H. Hermans, P.F. Velden, van

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Abstract

During the detn. of minute amts. of amino acids by the method of Sanger (C.A. 40, 5399.4), polymers (usually up to the tetramer) were identified by their Rf values. Fluorodinitrobenzene, amino acids, and dinitrophenol amino acids must be present to produce polymerization. The proportion of dinitrophenyl amino acid dimer under equal reaction conditions is in the order glycine .mchlt. b-alanine <e-aminocaproic acid .apprx. w-aminoheptanoic acid .apprx. w-aminoundecanoic acid. Certain losses in quant. dinitrophenylation may be due to polymerization.

Original language	English
Pages (from-to)	1187-1188
Number of pages	2
Journal	Nature
Volume	174
DOIs	https://doi.org/10.1038/1741187b0
Publication status	Published - 1954

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title = "Polymerization reactions occurring during dinitrophenylation of a-, b-, and w-amino acids with Sanger's reagent",

abstract = "During the detn. of minute amts. of amino acids by the method of Sanger (C.A. 40, 5399.4), polymers (usually up to the tetramer) were identified by their Rf values. Fluorodinitrobenzene, amino acids, and dinitrophenol amino acids must be present to produce polymerization. The proportion of dinitrophenyl amino acid dimer under equal reaction conditions is in the order glycine .mchlt. b-alanine <e-aminocaproic acid .apprx. w-aminoheptanoic acid .apprx. w-aminoundecanoic acid. Certain losses in quant. dinitrophenylation may be due to polymerization.",

author = "D. Heikens and P.H. Hermans and {Velden, van}, P.F.",

year = "1954",

doi = "10.1038/1741187b0",

language = "English",

volume = "174",

pages = "1187--1188",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Publishing Group",

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TY - JOUR

T1 - Polymerization reactions occurring during dinitrophenylation of a-, b-, and w-amino acids with Sanger's reagent

AU - Heikens, D.

AU - Hermans, P.H.

AU - Velden, van, P.F.

PY - 1954

Y1 - 1954

N2 - During the detn. of minute amts. of amino acids by the method of Sanger (C.A. 40, 5399.4), polymers (usually up to the tetramer) were identified by their Rf values. Fluorodinitrobenzene, amino acids, and dinitrophenol amino acids must be present to produce polymerization. The proportion of dinitrophenyl amino acid dimer under equal reaction conditions is in the order glycine .mchlt. b-alanine <e-aminocaproic acid .apprx. w-aminoheptanoic acid .apprx. w-aminoundecanoic acid. Certain losses in quant. dinitrophenylation may be due to polymerization.

AB - During the detn. of minute amts. of amino acids by the method of Sanger (C.A. 40, 5399.4), polymers (usually up to the tetramer) were identified by their Rf values. Fluorodinitrobenzene, amino acids, and dinitrophenol amino acids must be present to produce polymerization. The proportion of dinitrophenyl amino acid dimer under equal reaction conditions is in the order glycine .mchlt. b-alanine <e-aminocaproic acid .apprx. w-aminoheptanoic acid .apprx. w-aminoundecanoic acid. Certain losses in quant. dinitrophenylation may be due to polymerization.

U2 - 10.1038/1741187b0

DO - 10.1038/1741187b0

M3 - Article

SN - 0028-0836

VL - 174

SP - 1187

EP - 1188

JO - Nature

JF - Nature

ER -

Polymerization reactions occurring during dinitrophenylation of a-, b-, and w-amino acids with Sanger's reagent

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