Polymeric antibubbles with strong ultrasound imaging capabilities

Roman A. Barmin; Jens Köhler; Michael Pohl; Bea Becker; Fabian Kiessling; Twan Lammers; Albert T. Poortinga; Roger M. Pallares

doi:10.1039/d4cc03572k

Polymeric antibubbles with strong ultrasound imaging capabilities

Roman A. Barmin
, Jens Köhler
, Michael Pohl
, Bea Becker
, Fabian Kiessling
, Twan Lammers (Corresponding author)
, Albert T. Poortinga (Corresponding author)
, Roger M. Pallares (Corresponding author)

Research output: Contribution to journal › Article › Academic › peer-review

6 Citations (Scopus)

33 Downloads (Pure)

Abstract

Antibubbles are liquid droplets encapsulated by a gas film that have recently been explored for on-demand ultrasound-triggered drug release. However, their ultrasound imaging capabilities are limited by their stiff shells stabilized with silica nanoparticles. Here, we develop polymeric antibubbles that generate greater ultrasound contrast than silica-based antibubbles, while showing better stability than conventional polymeric microbubbles.

Original language	English
Pages (from-to)	13340-13343
Number of pages	4
Journal	Chemical Communications
Volume	60
Issue number	91
Early online date	27 Sept 2024
DOIs	https://doi.org/10.1039/d4cc03572k
Publication status	Published - 25 Nov 2024

Bibliographical note

Publisher Copyright:
© 2024 The Royal Society of Chemistry.

Funding

Funders	Funder number
European Union's Horizon 2020 - Research and Innovation Framework Programme	864121

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10.1039/d4cc03572k

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Cite this

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AU - Barmin, Roman A.

AU - Köhler, Jens

AU - Pohl, Michael

AU - Becker, Bea

AU - Kiessling, Fabian

AU - Lammers, Twan

AU - Poortinga, Albert T.

AU - Pallares, Roger M.

PY - 2024/11/25

Y1 - 2024/11/25

N2 - Antibubbles are liquid droplets encapsulated by a gas film that have recently been explored for on-demand ultrasound-triggered drug release. However, their ultrasound imaging capabilities are limited by their stiff shells stabilized with silica nanoparticles. Here, we develop polymeric antibubbles that generate greater ultrasound contrast than silica-based antibubbles, while showing better stability than conventional polymeric microbubbles.

AB - Antibubbles are liquid droplets encapsulated by a gas film that have recently been explored for on-demand ultrasound-triggered drug release. However, their ultrasound imaging capabilities are limited by their stiff shells stabilized with silica nanoparticles. Here, we develop polymeric antibubbles that generate greater ultrasound contrast than silica-based antibubbles, while showing better stability than conventional polymeric microbubbles.

UR - https://www.scopus.com/pages/publications/85205439938

U2 - 10.1039/d4cc03572k

DO - 10.1039/d4cc03572k

M3 - Article

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VL - 60

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JO - Chemical Communications

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IS - 91

ER -

Polymeric antibubbles with strong ultrasound imaging capabilities

Abstract

Bibliographical note

Funding

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