We present a polymer optical waveguide integration technology for the detection of nanoparticles in an evanescent field based biosensor. In the proposed biosensor concept, super-paramagnetic nanoparticles are used as optical contrast labels. The nanoparticles capture target molecules from a sample fluid and bind to the sensor surface with biological specificity. The surface-bound nanoparticles are then detected using frustration of an evanescent field. In the current paper we elaborate on the polymer waveguides which are used to generate a well-defined optical field for nanoparticle detection.
|Title of host publication||SPIE Photonics West : Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI, 20 February 2014|
|Editors||A.N. Cartwright, D.V. Nicolau|
|Place of Publication||Bellingham|
|Publication status||Published - 2010|
|Name||Proceedings of SPIE|