Polymer slab waveguides for the optical detection of nanoparticles in evanescent field based biosensors

N. Teigell Beneitez, J. Missinne, J.J.H.B. Schleipen, J.G. Orsel, M.W.J. Prins, G. Steenberge, Van

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

2 Citations (Scopus)
143 Downloads (Pure)

Abstract

We present a polymer optical waveguide integration technology for the detection of nanoparticles in an evanescent field based biosensor. In the proposed biosensor concept, super-paramagnetic nanoparticles are used as optical contrast labels. The nanoparticles capture target molecules from a sample fluid and bind to the sensor surface with biological specificity. The surface-bound nanoparticles are then detected using frustration of an evanescent field. In the current paper we elaborate on the polymer waveguides which are used to generate a well-defined optical field for nanoparticle detection.
Original languageEnglish
Title of host publicationSPIE Photonics West : Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI, 20 February 2014
EditorsA.N. Cartwright, D.V. Nicolau
Place of PublicationBellingham
PublisherSPIE
Pages89540Q-1/7
DOIs
Publication statusPublished - 2010

Publication series

NameProceedings of SPIE
Volume8954
ISSN (Print)0277-786X

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