Phase transfer catalysis in a microchannel: fluidic control of conversion and selectivity

J. Jovanovic, E.V. Rebrov, T.A. Nijhuis, V. Hessel, J.C. Schouten

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Precise control over the segmented flow in a microchannel reactor offers an important tool for the optimization of reaction yield and productivity. The fluidic control over the reaction was demonstrated on the selective alkylation of benzyl cyanide to the monoalkylated product in a 250 µm microchannel reactor. The conversion of benzyl cyanide increased from 39.9% to 99.7% as a result of a 97% larger slug surface-to-volume ratio when the volumetric aqueous-to-organic phase flow ratio was raised from 1.0 to 6.1 at the same residence time. Conversion and selectivity in the microchannel reactor are both significantly larger than in a stirred reactor.
Original languageEnglish
Title of host publicationProceedings of the 11th International Conference on Microreaction Technology (IMRET 11), March 8-10 March 2010, Kyoto Japan
Pages116-117
Publication statusPublished - 2010
Event11th International Conference on Microreaction Technology (IMRET 11), March 8-10, 2010, Kyoto, Japan - Kyoto, Japan
Duration: 8 Mar 201010 Mar 2010

Conference

Conference11th International Conference on Microreaction Technology (IMRET 11), March 8-10, 2010, Kyoto, Japan
Abbreviated titleIMRET 11
CountryJapan
CityKyoto
Period8/03/1010/03/10

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