Patients with psychogenic non-epileptic seizures referred to a tertiary epilepsy centre: patient characteristics in relation to diagnostic delay

N.M.G Bodde, R.H.C. Lazeron, J.M.A. Wirken, S.J.M. van der Kruijs, A.P. Aldenkamp, P. Boon

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Abstract

Objective: This clinical study examines patient and seizure characteristics of patients with psychogenic non-epileptic seizures (PNES) in a tertiary epilepsy centre. The main focus was whether a new subgroup of PNES patients emerged with a relatively short referral time and possible specific characteristics. Methods: All PNES patients referred to a specialist program in our centre between mid 2007 and mid 2009 were consecutively included. This yielded a study cohort of 90 patients. Results: The majority of the patients have a patient history with many medical symptoms and they were or had been in treatment by a medical specialist. Furthermore diffuse psychological/psychiatric symptoms and subsequent treatments are also remarkably common, in general without a clear psychological diagnosis. The average time between seizure onset and referral to an epilepsy centre is remarkably low (4.29 years). About 50% of the patients were referred within 2 years of seizure onset. This 'active high speed referral group' had significantly more previous psychological complaints, significantly more previous psychological/psychiatric treatments and a trend towards more previous medical investigations. Conclusion: There seems to be a new subgroup of PNES patients with a short referral time, characterized by a more active attitude towards examination of the symptoms in combination with an active attitude to apply for treatment. However, the PNES cohort as a whole is characterized by having somatoform symptoms based on a process of somatization.

Original languageEnglish
Pages (from-to)217-222
Number of pages6
JournalClinical Neurology and Neurosurgery
Volume114
Issue number3
DOIs
Publication statusPublished - Apr 2012
Externally publishedYes

Fingerprint

Epilepsy
Seizures
Referral and Consultation
Psychology
Psychiatry
Therapeutics
Cohort Studies

Keywords

  • Delayed diagnosis
  • Non-epileptic attack disorder
  • Patient characteristics
  • Patient history
  • Psychiatric comorbidity
  • Referral patterns
  • Somatoform disorders

Cite this

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title = "Patients with psychogenic non-epileptic seizures referred to a tertiary epilepsy centre: patient characteristics in relation to diagnostic delay",
abstract = "Objective: This clinical study examines patient and seizure characteristics of patients with psychogenic non-epileptic seizures (PNES) in a tertiary epilepsy centre. The main focus was whether a new subgroup of PNES patients emerged with a relatively short referral time and possible specific characteristics. Methods: All PNES patients referred to a specialist program in our centre between mid 2007 and mid 2009 were consecutively included. This yielded a study cohort of 90 patients. Results: The majority of the patients have a patient history with many medical symptoms and they were or had been in treatment by a medical specialist. Furthermore diffuse psychological/psychiatric symptoms and subsequent treatments are also remarkably common, in general without a clear psychological diagnosis. The average time between seizure onset and referral to an epilepsy centre is remarkably low (4.29 years). About 50{\%} of the patients were referred within 2 years of seizure onset. This 'active high speed referral group' had significantly more previous psychological complaints, significantly more previous psychological/psychiatric treatments and a trend towards more previous medical investigations. Conclusion: There seems to be a new subgroup of PNES patients with a short referral time, characterized by a more active attitude towards examination of the symptoms in combination with an active attitude to apply for treatment. However, the PNES cohort as a whole is characterized by having somatoform symptoms based on a process of somatization.",
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Patients with psychogenic non-epileptic seizures referred to a tertiary epilepsy centre: patient characteristics in relation to diagnostic delay. / Bodde, N.M.G; Lazeron, R.H.C.; Wirken, J.M.A.; van der Kruijs, S.J.M.; Aldenkamp, A.P.; Boon, P.

In: Clinical Neurology and Neurosurgery, Vol. 114, No. 3, 04.2012, p. 217-222.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - Patients with psychogenic non-epileptic seizures referred to a tertiary epilepsy centre: patient characteristics in relation to diagnostic delay

AU - Bodde, N.M.G

AU - Lazeron, R.H.C.

AU - Wirken, J.M.A.

AU - van der Kruijs, S.J.M.

AU - Aldenkamp, A.P.

AU - Boon, P.

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KW - Referral patterns

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