Organoids in endocrine and metabolic research: current and emerging applications

Penney M. Gilbert, Sandra Hofmann, Huck Hui Ng, Hugo Vankelecom, James M. Wells

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Organoid technologies are a potent tool for investigating human biology, modelling diseases and developing novel therapies. In this Viewpoint, experts in metabolic and endocrine research in the brain, pituitary, skeletal muscle, bone and gastrointestinal system discuss how organoids and related bioengineered systems are currently used in their field and how innovations in these technologies could transform future research.

Original languageEnglish
Pages (from-to)195-201
Number of pages7
JournalNature Reviews. Endocrinology
Volume20
Issue number4
Early online date5 Jan 2024
DOIs
Publication statusPublished - Apr 2024

Funding

P.M.G. is cross-appointed to the Donnelly Centre and to the Department of Cell and Systems Biology at the University of Toronto. H.H.N. is supported by grants from the Agency for Science, Technology and Research (A*STAR) and the National Medical Research Council of Singapore. H.H.N. is grateful to Dr Alfred Sun (Duke-NUS Medical School) for discussion during the preparation of this manuscript. H.V. was supported by grants from the KU Leuven Research Fund and the Fund for Scientific Research (FWO) – Flanders (Belgium).

FundersFunder number
Katholieke Universiteit Leuven
Agency for Science, Technology and Research (A*STAR)
National Health and Medical Research Council
Fonds De La Recherche Scientifique - FNRS
Fonds Wetenschappelijk Onderzoek

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