Optimization of pulsed wave tissue Doppler to predict left ventricular reverse remodeling after cardiac resynchronization therapy

A.H. Jansen, F.A.L.E. Bracke, J.M. Dantzig, van, H. Korsten, C.H. Peels, N.M. Hemel, van

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)

Abstract

OBJECTIVE: The optimal use of pulsed wave Doppler tissue imaging (DTI) in predicting left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT) was investigated. METHODS: DTI was performed in 69 patients before and 3 months after CRT. Echocardiographic reverse remodeling was observed in 38 patients. LV dyssynchrony was measured with the time to onset or peak systolic velocity in 2- and 6-basal segment models. RESULTS: The time to onset and either the standard deviation of 6 segments of > 20 ms or a delay of > or = 60 ms between any 2 of 6 segments had a similar predictive accuracy (sensitivity, 97% and 95%, respectively; specificity, 74% and 73%, respectively). The time to peak systolic velocity or evaluating 2 segments was less accurate. CONCLUSIONS: Evaluation of 6 segments is necessary to predict LV reverse remodeling after CRT. The time to onset of systolic velocity is superior to the time to peak velocity.
Original languageEnglish
Pages (from-to)185-191
Number of pages6
JournalJournal of the American Society of Echocardiography
Volume19
Issue number2
DOIs
Publication statusPublished - 2006

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