TY - JOUR
T1 - Optimization of basic parameters in temperature-programmed gas chromatographic separations of multi-component samples within a given time
AU - Repka, D.
AU - Krupcik, J.
AU - Brunovska, A.
AU - Leclercq, P.A.
AU - Rijks, J.A.
PY - 1989
Y1 - 1989
N2 - A new procedure is introduced for the optimization of column peak capacity in a given time. The opitmization focuses on temperature-programmed operating conditions, notably the initial temperature and hold time, and the programming rate. Based conceptually upon Lagrange functions, experiments were carried out long simplex sequential and central composite design procedures. The validity of the theory was demonstrated by separations of some crude oil distillation fractions.
AB - A new procedure is introduced for the optimization of column peak capacity in a given time. The opitmization focuses on temperature-programmed operating conditions, notably the initial temperature and hold time, and the programming rate. Based conceptually upon Lagrange functions, experiments were carried out long simplex sequential and central composite design procedures. The validity of the theory was demonstrated by separations of some crude oil distillation fractions.
U2 - 10.1016/S0021-9673(01)84478-2
DO - 10.1016/S0021-9673(01)84478-2
M3 - Article
SN - 0021-9673
VL - 463
SP - 235
EP - 242
JO - Journal of Chromatography
JF - Journal of Chromatography
IS - 2
ER -