Optical resolution of DL-amino acids by ligand exchange : I. a study of the resolution of DL-aspartic acid with the aid of copper complexes of L(a)-alanine

J.J.H. Kan, Van, J.J.P.M. Bachus

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    Abstract

    Spectrophotometric studies were made of the reaction of the Cu complexes of L-alanine with DL-aspartic acid to give a ppt. of a Cu-D-aspartic acid complex, and the effects of stirring, addn. of NaClO4 as supporting electrolyte, pH, and temp. on the quantity of the complex pptd. were detd. Both L- and D-aspartic acid react with the Cu-L-alanine complex, and the Cu-D-aspartic acid complex pptd. is nonstoichiometric with no evidence of Cu-Cu bonds. After pptn. of the Cu-D-aspartic acid complex, a Cu-L-aspartic acid complex is pptd. Resoln. occurs only between pH 2.7 and 5.3, and the specificity of resoln. is detd. by kinetics rather than by thermodynamics. [on SciFinder (R)]
    Original languageEnglish
    Pages (from-to)159-161
    JournalJournal of Applied Chemistry
    Volume20
    Issue number5
    Publication statusPublished - 1970

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    D-Aspartic Acid
    Aspartic Acid
    Alanine
    Copper
    Ligands
    Amino Acids
    Electrolytes
    Thermodynamics
    Kinetics

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    @article{5e3b2a471ae84f35aed1f38ebeddd698,
    title = "Optical resolution of DL-amino acids by ligand exchange : I. a study of the resolution of DL-aspartic acid with the aid of copper complexes of L(a)-alanine",
    abstract = "Spectrophotometric studies were made of the reaction of the Cu complexes of L-alanine with DL-aspartic acid to give a ppt. of a Cu-D-aspartic acid complex, and the effects of stirring, addn. of NaClO4 as supporting electrolyte, pH, and temp. on the quantity of the complex pptd. were detd. Both L- and D-aspartic acid react with the Cu-L-alanine complex, and the Cu-D-aspartic acid complex pptd. is nonstoichiometric with no evidence of Cu-Cu bonds. After pptn. of the Cu-D-aspartic acid complex, a Cu-L-aspartic acid complex is pptd. Resoln. occurs only between pH 2.7 and 5.3, and the specificity of resoln. is detd. by kinetics rather than by thermodynamics. [on SciFinder (R)]",
    author = "{Kan, Van}, J.J.H. and J.J.P.M. Bachus",
    year = "1970",
    language = "English",
    volume = "20",
    pages = "159--161",
    journal = "Journal of Applied Chemistry",
    issn = "0021-8871",
    number = "5",

    }

    Optical resolution of DL-amino acids by ligand exchange : I. a study of the resolution of DL-aspartic acid with the aid of copper complexes of L(a)-alanine. / Kan, Van, J.J.H.; Bachus, J.J.P.M.

    In: Journal of Applied Chemistry, Vol. 20, No. 5, 1970, p. 159-161.

    Research output: Contribution to journalArticleAcademicpeer-review

    TY - JOUR

    T1 - Optical resolution of DL-amino acids by ligand exchange : I. a study of the resolution of DL-aspartic acid with the aid of copper complexes of L(a)-alanine

    AU - Kan, Van, J.J.H.

    AU - Bachus, J.J.P.M.

    PY - 1970

    Y1 - 1970

    N2 - Spectrophotometric studies were made of the reaction of the Cu complexes of L-alanine with DL-aspartic acid to give a ppt. of a Cu-D-aspartic acid complex, and the effects of stirring, addn. of NaClO4 as supporting electrolyte, pH, and temp. on the quantity of the complex pptd. were detd. Both L- and D-aspartic acid react with the Cu-L-alanine complex, and the Cu-D-aspartic acid complex pptd. is nonstoichiometric with no evidence of Cu-Cu bonds. After pptn. of the Cu-D-aspartic acid complex, a Cu-L-aspartic acid complex is pptd. Resoln. occurs only between pH 2.7 and 5.3, and the specificity of resoln. is detd. by kinetics rather than by thermodynamics. [on SciFinder (R)]

    AB - Spectrophotometric studies were made of the reaction of the Cu complexes of L-alanine with DL-aspartic acid to give a ppt. of a Cu-D-aspartic acid complex, and the effects of stirring, addn. of NaClO4 as supporting electrolyte, pH, and temp. on the quantity of the complex pptd. were detd. Both L- and D-aspartic acid react with the Cu-L-alanine complex, and the Cu-D-aspartic acid complex pptd. is nonstoichiometric with no evidence of Cu-Cu bonds. After pptn. of the Cu-D-aspartic acid complex, a Cu-L-aspartic acid complex is pptd. Resoln. occurs only between pH 2.7 and 5.3, and the specificity of resoln. is detd. by kinetics rather than by thermodynamics. [on SciFinder (R)]

    M3 - Article

    VL - 20

    SP - 159

    EP - 161

    JO - Journal of Applied Chemistry

    JF - Journal of Applied Chemistry

    SN - 0021-8871

    IS - 5

    ER -