Abstract
A series of palladium acyclic diaminocarbene (ADC) complexes of the type cis-[(R1NH)(R2)methylidene]- PdCl2(CNR1) [R1 = 2, 4, 6-(CH3)3C6H2: R2 = NC5 H10 (2); NC4H8 (3); NC4H8O (4)] were used not only to perform the Csp2-Csp Hiyama coupling between aryl iodide and triethoxysilylalkynes but also to subsequently carry out the one-pot tandem Hiyama alkynylation/cyclization reaction between 2- iodophenol and triethoxysilylalkynes, giving a convenient timeefficient access to the biologically relevant benzofuran compounds. The palladium ADC complexes (2-4) were conveniently synthesized by the nucleophilic addition of secondary amines, namely, piperidine, pyrrolidine, and morpholine on the cis-{(2, 4, 6-(CH3)3C6H2)NC}2PdCl2 in moderate yields (ca. 61-66%) .
| Original language | English |
|---|---|
| Pages (from-to) | 1740-1756 |
| Number of pages | 17 |
| Journal | ACS Omega |
| Volume | 3 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 9 Feb 2018 |
| Externally published | Yes |
Bibliographical note
Funding Information:We thank the Department of Science and Technology (EMR/ 2014/000254), New Delhi, India, for financial support of this research. We gratefully acknowledge Single Crystal X-ray Diffraction Facility, Department of Chemistry, IIT Bombay, Mumbai, India, for the crystallographic characterization data. C.S., A.P.P. and M.K.G., thank CSIR, New Delhi, India, for research fellowships.
Publisher Copyright:
© 2018 American Chemical Society.
Funding
We thank the Department of Science and Technology (EMR/ 2014/000254), New Delhi, India, for financial support of this research. We gratefully acknowledge Single Crystal X-ray Diffraction Facility, Department of Chemistry, IIT Bombay, Mumbai, India, for the crystallographic characterization data. C.S., A.P.P. and M.K.G., thank CSIR, New Delhi, India, for research fellowships.