On the role of mitochondrial creatine kinase and VDAC in mitochondrial function of heart muscle cells

F. Veld, ter, F.J. Bruggeman, J.A.L. Jeneson, K. Nicolaij

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

A two-compartment kinetic model was used to describe reconstituted systems in which mitochondria compete with pyruvate kinase for kinase-generated ADP. The modelling suggests that cytosolic CK deficiency results in a 50% increase in outer mitochondrial membrane permeability.
Original languageEnglish
Pages (from-to)183-186
JournalMolecular Biology Reports
Volume29
Issue number1/2
DOIs
Publication statusPublished - 2002

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