Abstract
Numerous researchers have found that capillary vessel haematocrit depends on the vasodilatory state of the arterioles. At rest, vessel haematocrit is down to 15 %, suggesting a red blood cell velocity three times higher than the plasma velocity. This finding is analysed in the context of present understanding of propulsion of red blood cells (RBCs) and plasma by means of the arteriovenous pressure gradient. Interfacial forces between the red blood cells and the plasma are proposed as a rational explanation of the observed red blood cell velocities. While the arteriovenous pressure gradient across the capillaries propels the red blood cell and the plasma jointly, interfacial forces along the red blood cell membrane can propel RBCs at the cost of the plasma. Different options are explored for the physical origin of these interfacial forces and oxygen gradients are found to be the most probable source.
| Language | English |
|---|---|
| Title of host publication | Advances in Experimental Medicine and Biology |
| Place of Publication | Cham |
| Publisher | Springer |
| Pages | 191-200 |
| Number of pages | 10 |
| ISBN (Electronic) | 978-3-319-96445-4 |
| ISBN (Print) | 978-3-319-96444-7 |
| DOIs | |
| State | Published - 1 Jan 2018 |
Publication series
| Name | Advances in Experimental Medicine and Biology |
|---|---|
| Volume | 1097 |
| ISSN (Print) | 0065-2598 |
| ISSN (Electronic) | 2214-8019 |
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On the physics underlying longitudinal capillary recruitment. / Huyghe, Jacques M.
Advances in Experimental Medicine and Biology. Cham : Springer, 2018. p. 191-200 (Advances in Experimental Medicine and Biology; Vol. 1097).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
TY - CHAP
T1 - On the physics underlying longitudinal capillary recruitment
AU - Huyghe,Jacques M.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Numerous researchers have found that capillary vessel haematocrit depends on the vasodilatory state of the arterioles. At rest, vessel haematocrit is down to 15 %, suggesting a red blood cell velocity three times higher than the plasma velocity. This finding is analysed in the context of present understanding of propulsion of red blood cells (RBCs) and plasma by means of the arteriovenous pressure gradient. Interfacial forces between the red blood cells and the plasma are proposed as a rational explanation of the observed red blood cell velocities. While the arteriovenous pressure gradient across the capillaries propels the red blood cell and the plasma jointly, interfacial forces along the red blood cell membrane can propel RBCs at the cost of the plasma. Different options are explored for the physical origin of these interfacial forces and oxygen gradients are found to be the most probable source.
AB - Numerous researchers have found that capillary vessel haematocrit depends on the vasodilatory state of the arterioles. At rest, vessel haematocrit is down to 15 %, suggesting a red blood cell velocity three times higher than the plasma velocity. This finding is analysed in the context of present understanding of propulsion of red blood cells (RBCs) and plasma by means of the arteriovenous pressure gradient. Interfacial forces between the red blood cells and the plasma are proposed as a rational explanation of the observed red blood cell velocities. While the arteriovenous pressure gradient across the capillaries propels the red blood cell and the plasma jointly, interfacial forces along the red blood cell membrane can propel RBCs at the cost of the plasma. Different options are explored for the physical origin of these interfacial forces and oxygen gradients are found to be the most probable source.
UR - http://www.scopus.com/inward/record.url?scp=85054898408&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-96445-4_10
DO - 10.1007/978-3-319-96445-4_10
M3 - Chapter
SN - 978-3-319-96444-7
T3 - Advances in Experimental Medicine and Biology
SP - 191
EP - 200
BT - Advances in Experimental Medicine and Biology
PB - Springer
CY - Cham
ER -