On the distinct molecular architectures of dipping- and spray-LbL films containing lipid vesicles

Pedro H.B. Aoki, Priscila Alessio, Diogo Volpati, Fernando V. Paulovich, Antonio Riul, Osvaldo N. Oliveira, Carlos J.L. Constantino

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Abstract

The introduction of spraying procedures to fabricate layer-by-layer (LbL) films has brought new possibilities for the control of molecular architectures and for making the LbL technique compliant with industrial processes. In this study we show that significantly distinct architectures are produced for dipping and spray-LbL films of the same components, which included DODAB/DPPG vesicles. The films differed notably in their thickness and stratified nature. The electrical response of the two types of films to aqueous solutions containing erythrosin was also different. With multidimensional projections we showed that the impedance for the DODAB/DPPG spray-LbL film is more sensitive to changes in concentration, being therefore more promising as sensing units. Furthermore, with surface-enhanced Raman scattering (SERS) we could ascribe the high sensitivity of the LbL films to adsorption of erythrosin.

Original languageEnglish
Pages (from-to)363-371
Number of pages9
JournalMaterials Science and Engineering C
Volume41
DOIs
Publication statusPublished - 1 Aug 2014

Bibliographical note

Funding Information:
This work was supported by FAPESP, CNPq and the nBioNet network from CAPES (Brazil).

Keywords

  • Erythrosin
  • Information visualization
  • Layer-by-layer films
  • Molecular architecture
  • Sensing

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