Abstract
Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2}q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37°C, and retarding clearance from circulation.
Original language | English |
---|---|
Patent number | WO2012172457 |
IPC | C07C 69/ 708 A I |
Priority date | 16/06/11 |
Publication status | Published - 20 Dec 2012 |