Abstract
Contemporary tissue engineered heart valves seem to have sufficient mechanical strength for implantation [1]. Nevertheless, mechanical properties, tissue structure and architecture still need to be improved. Recent studies indicate enhancement of mechanical properties by applying cyclic diastolic pressure loads to the developing tissue in a bioreactor system [2]. However, current bioreactors operate with a preset transvalvular pressure applied to the tissue. Mechanical properties of the engineered construct may vary during culturing and consequently, the pressure-induced deformations are unknown. To systematically study the effects of mechanical straining on tissue development and to design an optimal conditioning protocol, real-time measurement and control of local tissue strains are desired.
Original language | English |
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Title of host publication | Proceedings of the ASME 2007 Summer Bioengineering Conference (SBC 2007) 20-24 June 2007, Keystone, Colorado, USA |
Place of Publication | Keystone, Colorado, USA |
Pages | 143-144 |
DOIs | |
Publication status | Published - 2007 |
Event | ASME 2007 Summer Bioengineering Conference, SBC 2007 - Keystone, United States Duration: 20 Jun 2007 → 24 Jun 2007 |
Conference
Conference | ASME 2007 Summer Bioengineering Conference, SBC 2007 |
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Abbreviated title | SBC 2007 |
Country/Territory | United States |
City | Keystone |
Period | 20/06/07 → 24/06/07 |