Nieuwe therapeutische benadering van amyloïdose: vooralsnog geen implicaties voor patiënten met de ziekte van Alzheimer

A.W. Lemstra, P. Eikelenboom, E.W. Meijer, W.A. Gool, van

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Many disorders, such as Alzheimer's disease and diabetes, are characterised by the misfolding and aggregation of proteins. Pepys et al. described a new approach of destabilizing these aggregates by removing an associated protein, serum amyloid P. This offers opportunities for treating amyloidosis and possibly other protein folding diseases. Understanding the mechanism of this unique disease process and the different elements involved is necessary for future drug development.
Original languageDutch
Pages (from-to)1720-1723
JournalNederlands Tijdschrift voor Geneeskunde
Volume146
Issue number2
Publication statusPublished - 2002

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