Nature-inspired active micro-fluidic mixing using artificial cilia

Jaap M.J. den Toonder; Femke Bos; Dirk J. Broer; Murray Gillies; Judith de Goede; Titie Mol; Mireille Reijme; Wim Talen; Hans Wilderbeek; Viny Khatavkar; Patrick Anderson

Nature-inspired active micro-fluidic mixing using artificial cilia

Jaap M.J. den Toonder, Femke Bos, Dirk J. Broer, Murray Gillies, Judith de Goede, Titie Mol, Mireille Reijme, Wim Talen, Hans Wilderbeek, Viny Khatavkar, Patrick Anderson

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Abstract

Creating good mixing flows in lab-on-chip systems poses a special challenge, due to the impossibility to generate turbulence. We propose a novel concept for active mixing, that is inspired by nature, namely micro-organisms that swim through a liquid by beating microscopic hairs, cilia, covering their surface. We have fabricated artificial cilia, based on electro-statically actuated polymer structures, and have integrated these in a micro-fluidic channel. Flow visualization experiments show that our cilia can generate very efficient mixing. Since the artificial cilia can be actively controlled using an electrical signal, they have exciting applications in micro-fluidic devices.

Original language	English
Title of host publication	Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Editors	Jean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
Publisher	Chemical and Biological Microsystems Society
Pages	1143-1145
Number of pages	3
ISBN (Electronic)	9780979806407
Publication status	Published - 2007
Event	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France Duration: 7 Oct 2007 → 11 Oct 2007

Conference

Conference	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/Territory	France
City	Paris
Period	7/10/07 → 11/10/07

Keywords

Active mixing
Artificial cilia
Micro-fluidics
Polymer actuators

Cite this

den Toonder, J. M. J., Bos, F., Broer, D. J., Gillies, M., de Goede, J., Mol, T., Reijme, M., Talen, W., Wilderbeek, H., Khatavkar, V., & Anderson, P. (2007). Nature-inspired active micro-fluidic mixing using artificial cilia. In J-L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 (pp. 1143-1145). Chemical and Biological Microsystems Society.

den Toonder, Jaap M.J. ; Bos, Femke ; Broer, Dirk J. et al. / Nature-inspired active micro-fluidic mixing using artificial cilia. Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. editor / Jean-Louis Viovy ; Patrick Tabeling ; Stephanie Descroix ; Laurent Malaquin. Chemical and Biological Microsystems Society, 2007. pp. 1143-1145

@inproceedings{51db962d36fd44eeac1075169615a2bd,

title = "Nature-inspired active micro-fluidic mixing using artificial cilia",

abstract = "Creating good mixing flows in lab-on-chip systems poses a special challenge, due to the impossibility to generate turbulence. We propose a novel concept for active mixing, that is inspired by nature, namely micro-organisms that swim through a liquid by beating microscopic hairs, cilia, covering their surface. We have fabricated artificial cilia, based on electro-statically actuated polymer structures, and have integrated these in a micro-fluidic channel. Flow visualization experiments show that our cilia can generate very efficient mixing. Since the artificial cilia can be actively controlled using an electrical signal, they have exciting applications in micro-fluidic devices.",

keywords = "Active mixing, Artificial cilia, Micro-fluidics, Polymer actuators",

author = "{den Toonder}, {Jaap M.J.} and Femke Bos and Broer, {Dirk J.} and Murray Gillies and {de Goede}, Judith and Titie Mol and Mireille Reijme and Wim Talen and Hans Wilderbeek and Viny Khatavkar and Patrick Anderson",

year = "2007",

language = "English",

pages = "1143--1145",

editor = "Jean-Louis Viovy and Patrick Tabeling and Stephanie Descroix and Laurent Malaquin",

booktitle = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",

publisher = "Chemical and Biological Microsystems Society",

note = "11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 ; Conference date: 07-10-2007 Through 11-10-2007",

}

den Toonder, JMJ, Bos, F, Broer, DJ, Gillies, M, de Goede, J, Mol, T, Reijme, M, Talen, W, Wilderbeek, H, Khatavkar, V & Anderson, P 2007, Nature-inspired active micro-fluidic mixing using artificial cilia. in J-L Viovy, P Tabeling, S Descroix & L Malaquin (eds), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. Chemical and Biological Microsystems Society, pp. 1143-1145, 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, Paris, France, 7/10/07.

Nature-inspired active micro-fluidic mixing using artificial cilia. / den Toonder, Jaap M.J.; Bos, Femke; Broer, Dirk J. et al.
Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. ed. / Jean-Louis Viovy; Patrick Tabeling; Stephanie Descroix; Laurent Malaquin. Chemical and Biological Microsystems Society, 2007. p. 1143-1145.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Nature-inspired active micro-fluidic mixing using artificial cilia

AU - den Toonder, Jaap M.J.

AU - Bos, Femke

AU - Broer, Dirk J.

AU - Gillies, Murray

AU - de Goede, Judith

AU - Mol, Titie

AU - Reijme, Mireille

AU - Talen, Wim

AU - Wilderbeek, Hans

AU - Khatavkar, Viny

AU - Anderson, Patrick

PY - 2007

Y1 - 2007

N2 - Creating good mixing flows in lab-on-chip systems poses a special challenge, due to the impossibility to generate turbulence. We propose a novel concept for active mixing, that is inspired by nature, namely micro-organisms that swim through a liquid by beating microscopic hairs, cilia, covering their surface. We have fabricated artificial cilia, based on electro-statically actuated polymer structures, and have integrated these in a micro-fluidic channel. Flow visualization experiments show that our cilia can generate very efficient mixing. Since the artificial cilia can be actively controlled using an electrical signal, they have exciting applications in micro-fluidic devices.

AB - Creating good mixing flows in lab-on-chip systems poses a special challenge, due to the impossibility to generate turbulence. We propose a novel concept for active mixing, that is inspired by nature, namely micro-organisms that swim through a liquid by beating microscopic hairs, cilia, covering their surface. We have fabricated artificial cilia, based on electro-statically actuated polymer structures, and have integrated these in a micro-fluidic channel. Flow visualization experiments show that our cilia can generate very efficient mixing. Since the artificial cilia can be actively controlled using an electrical signal, they have exciting applications in micro-fluidic devices.

KW - Active mixing

KW - Artificial cilia

KW - Micro-fluidics

KW - Polymer actuators

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M3 - Conference contribution

AN - SCOPUS:85088679124

SP - 1143

EP - 1145

BT - Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

A2 - Viovy, Jean-Louis

A2 - Tabeling, Patrick

A2 - Descroix, Stephanie

A2 - Malaquin, Laurent

PB - Chemical and Biological Microsystems Society

T2 - 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Y2 - 7 October 2007 through 11 October 2007

ER -

den Toonder JMJ, Bos F, Broer DJ, Gillies M, de Goede J, Mol T et al. Nature-inspired active micro-fluidic mixing using artificial cilia. In Viovy J-L, Tabeling P, Descroix S, Malaquin L, editors, Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. Chemical and Biological Microsystems Society. 2007. p. 1143-1145

Nature-inspired active micro-fluidic mixing using artificial cilia

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