Mutual-information-based registration of medical images : a survey

J.P.W. Pluim, J.B.A. Maintz, M.A. Viergever

Research output: Contribution to journalArticleAcademicpeer-review

2262 Citations (Scopus)
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An overview is presented of the medical image processing literature on mutual-information-based registration. The aim of the survey is threefold: an introduction for those new to the field, an overview for those working in the field, and a reference for those searching for literature on a specific application. Methods are classified according to the different aspects of mutual-information-based registration. The main division is in aspects of the methodology and of the application. The part on methodology describes choices made on facets such as preprocessing of images, gray value interpolation, optimization, adaptations to the mutual information measure, and different types of geometrical transformations. The part on applications is a reference of the literature available on different modalities, on interpatient registration and on different anatomical objects. Comparison studies including mutual information are also considered. The paper starts with a description of entropy and mutual information and it closes with a discussion on past achievements and some future challenges.
Original languageEnglish
Pages (from-to)986-1004
Number of pages19
JournalIEEE Transactions on Medical Imaging
Issue number8
Publication statusPublished - 2003


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