Recent research suggests that “smart drugs” don’t make healthy individuals who use them smarter. The main effects are instead on levels of motivation and interest. So the main ethical question here is not whether there is anything wrong or regrettable about healthy individuals’ using these drugs to make themselves smarter. It is rather whether there is anything problematic about their using these drugs to control or modulate their levels of motivation and interest. This question can either be discussed on a wholly general level or be related to the values and goals characteristic of specific domains of human activity. This essay considers the use of motivation-modulators within the academic domain, and suggests two ways in which such enhancements might conflict with the values distinctive of this domain.