Motion patterns of tethered particles reveal heterogeneities on a molecular scale

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Abstract

Lab-on-chip biosensing systems based on actuated magnetic particles are set to realize integrated assays in which all assay steps are controlled and optimized by magnetic forces[1]. The particles capture analyte molecules and are bound to a surface using analyte-specific antibodies. We investigate the dynamics of such surface bound particles using Tethered Particle Motion (TPM). The experiments are performed with short DNA molecules (
Original languageEnglish
Title of host publicationDutch Physics Conference, Physics@FOM, 21-22 January 2014, Veldhoven, The Netherlands
Publication statusPublished - 2014
EventPhysics@FOM Veldhoven 2014 - Koningshof, Veldhoven, Netherlands
Duration: 21 Jan 201422 Jan 2014

Conference

ConferencePhysics@FOM Veldhoven 2014
Country/TerritoryNetherlands
CityVeldhoven
Period21/01/1422/01/14

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