Molecular encryption of DNA-encoded data in microcompartments

Highly advantageous means and methods are provided to protect data, i.e. through physical molecular encryption of nucleic-acid encoded data. Briefly, digital data, i.e. information is first encoded and designed into nucleic acid-encoded data; based on this nucleic acid-encoded data polynucleotide fragments are made. The nucleic acid encoded data is molecularly encrypted, i.e. molecularly locked. Molecularly locked means that access to the information in the nucleic acid encoded data, once converted into nucleic acid molecules, is blocked, which lockage can be unlocked by providing a specific unlocker, a molecule, that functions as a key to gain access to the nucleic acid.