Modular supramolecular ureidopyrimidinone polymer carriers for intracellular delivery

Maarten H. Bakker; Roxanne E. Kieltyka; Lorenzo Albertazzi; Patricia Y.W. Dankers

doi:10.1039/C6RA22490C

Modular supramolecular ureidopyrimidinone polymer carriers for intracellular delivery

Maarten H. Bakker, Roxanne E. Kieltyka, Lorenzo Albertazzi, Patricia Y.W. Dankers

Institute for Complex Molecular Systems

Research output: Contribution to journal › Article › Academic › peer-review

25 Citations (Scopus)

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Abstract

Ureidopyrimidinone-based polymers in solution provide a new platform for intracellular drug delivery. Here we show the synthesis of functional supramolecular polymers by mixing of monomers with various functionalities. Introduction of cationic monomers made them suitable for cellular uptake and siRNA delivery.

Original language	English
Pages (from-to)	110600-110603
Number of pages	4
Journal	RSC Advances
Volume	6
Issue number	112
DOIs	https://doi.org/10.1039/C6RA22490C
Publication status	Published - 1 Jan 2016

Funding

We thank the Ministry of Education, Culture and Science (Gravity program 024.001.035), the European Research Council (FP7/2007-2013) ERC Grant Agreement 308045, and the Netherlands Organization for Scientific Research (NWO-VENI Grant: 722.014.010) for funding.

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title = "Modular supramolecular ureidopyrimidinone polymer carriers for intracellular delivery",

abstract = "Ureidopyrimidinone-based polymers in solution provide a new platform for intracellular drug delivery. Here we show the synthesis of functional supramolecular polymers by mixing of monomers with various functionalities. Introduction of cationic monomers made them suitable for cellular uptake and siRNA delivery.",

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AU - Albertazzi, Lorenzo

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Modular supramolecular ureidopyrimidinone polymer carriers for intracellular delivery

Abstract

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