Modular supramolecular ureidopyrimidinone polymer carriers for intracellular delivery

Maarten H. Bakker, Roxanne E. Kieltyka, Lorenzo Albertazzi, Patricia Y.W. Dankers

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)
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Abstract

Ureidopyrimidinone-based polymers in solution provide a new platform for intracellular drug delivery. Here we show the synthesis of functional supramolecular polymers by mixing of monomers with various functionalities. Introduction of cationic monomers made them suitable for cellular uptake and siRNA delivery.

Original languageEnglish
Pages (from-to)110600-110603
Number of pages4
JournalRSC Advances
Volume6
Issue number112
DOIs
Publication statusPublished - 1 Jan 2016

Funding

We thank the Ministry of Education, Culture and Science (Gravity program 024.001.035), the European Research Council (FP7/2007-2013) ERC Grant Agreement 308045, and the Netherlands Organization for Scientific Research (NWO-VENI Grant: 722.014.010) for funding.

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