Modeling a heart pump

V. Creigen, L. Ferracina, A.V. Hlod, S. Mourik, van, K. Sjauw, V. Rottschäfer, M. Vellekoop, P.A. Zegeling

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review


In patients with acute heart failure, the heart can be assisted by the insertion of a mechanical device which takes over part of the heart’s work load by pumping blood from the left ventricle, one of the heart chambers, into the aorta. In this project, we formulate a model that describes the effect of such a device on the cardiovascular dynamics. We show that data for the pressure–volume relationship within a heart chamber that have been obtained experimentally can be reproduced quite accurately by our model. Moreover, such experimental data can help in calibrating unknown parameters that specify the characteristics of the pump. A key parameter turned out to be the extra friction that is encountered by the blood flowing through the heart pump.
Original languageEnglish
Title of host publicationProceedings 58th European Study Group Mathematics with Industry (ESGI58/SWI2007), 29 January - 2 February 2007, Utrecht, The Netherlands
EditorsR.H. Bisseling, K. Dajani, T.J. Dijkema, J. Leur, van de, P.A. Zegeling
Place of PublicationUtrecht
PublisherUtrecht University
Publication statusPublished - 2007


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