Minimum analysis time in capillary gas chromatography : vacuum- versus atmospheric-outlet column operation

P.A. Leclercq, C.A.M.G. Cramers

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Abstract

Previous studies on open tubular column operation at vacuum outlet vs. atmospheric outlet pressures focussed on comparisons of given columns, or comparisons of columns with the same inner diameters. It was demonstrated that, for a given separation problem, vacuum outlet operation of columns with a constant i.d. always yields the shortest analysis times (under minimum plate height conditions). In this paper, the comparison of vacuum vs. atmospheric outlet operation is broadened to columns with different dimensions. A general equation for tbe gain in speed of analysis by vacuum outlet operation of any column, as compared to atmospheric outlet operation of all possible open tubular columns with the same maximum plate number is presented. The resulting equation is further evaluated for thin film columns of different dimensions. It appears that vacuum outlet operation is beneficial only, in terms of speed of analysis, if low maximum plate numbers are required. The gain in speed of analysis is more pronounced for wide-bore than for narrow-bore columns.
Original languageEnglish
Title of host publicationEighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987
EditorsP. Sandra
Place of PublicationHeidelberg
PublisherHuethig
Pages72-82
Volume1
Publication statusPublished - 1987
Event8th International Symposium on Capillary Chromatography, 1987 - Palazzo dei Congressi, Riva del Garda, Italy
Duration: 19 May 198721 May 1987

Conference

Conference8th International Symposium on Capillary Chromatography, 1987
CountryItaly
CityRiva del Garda
Period19/05/8721/05/87

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