Method of and system for the automatic registration of anatomically corresponding positions for perfusion measurements

An automatic quantitative analysis method is developed so as to analyze perfusion cardiovascular images. First the image registration per data set is performed so as to compensate for translation and rotation of the target region of interest over the acquisition time. Next a parameter, for example, a maximum intensity projection, is calculated in order to average out misalignments of the target region of interest within each data set. Finally, parameter registration is performed to calculate the co-ordinate translation matrix between the anatomically corresponding pixels within the target region of interest. The co-ordinate translation matrix can also be used to calculate local perfusion values.