Membrane mediated sorting

T. Idema, S. Semrau, C. Storm, T. Schmidt

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
157 Downloads (Pure)


Inclusions in biological membranes may interact via deformations they induce on the shape of that very membrane. Such deformations are a purely physical effect, resulting in nonspecific forces between the inclusions. In this Letter we show that this type of interaction can organize membrane domains and hence may play an important biological role. Using a simple analytical model we predict that membrane inclusions sort according to the curvature they impose. We verify this prediction by both numerical simulations and experimental observations of membrane domains in phase separated vesicles.
Original languageEnglish
Article number198102
Pages (from-to)198102-1/4
Number of pages4
JournalPhysical Review Letters
Issue number19
Publication statusPublished - 2010


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