Mechanical properties of brain tissue: characterisation and constitutive modelling

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

The head is often considered as the most critical region of the human body for life-threatening injuries sustained in accidents. In order to develop effective protective measures, a better understanding of the process of injury development in the brain is required. Finite Element (FE) models are being developed, in order to predict the mechanical response of the contents of the head during impact. To obtain accurate predictions of the mechanical response of the brain, an accurate description of the mechanical behaviour of brain tissue is required. However, up to now no universally accepted data set for the constitutive response of brain tissue exists. The large variation in material properties reported may be caused by differences in testing methods and protocols used. An overview of studies on the mechanical properties of brain tissue is presented, focusing on testing methods. Furthermore, the large strain mechanical response of brain tissue as well as modelling approaches for this behaviour are discussed.
Original languageEnglish
Title of host publicationMechanosensitivity of the nervous system
EditorsA. Kamkin, I. Kiseleva
Place of PublicationBerlin
PublisherSpringer
Pages249-279
ISBN (Print)978-1-4020-8715-8
DOIs
Publication statusPublished - 2009

Publication series

NameMechanosensitivity in Cells and Tissues
Volume2

Fingerprint

Brain
Tissue
Mechanical properties
Testing
Materials properties
Accidents

Cite this

Dommelen, van, J. A. W., Hrapko, M., & Peters, G. W. M. (2009). Mechanical properties of brain tissue: characterisation and constitutive modelling. In A. Kamkin, & I. Kiseleva (Eds.), Mechanosensitivity of the nervous system (pp. 249-279). (Mechanosensitivity in Cells and Tissues; Vol. 2). Berlin: Springer. https://doi.org/10.1007/978-1-4020-8716-5_12
Dommelen, van, J.A.W. ; Hrapko, M. ; Peters, G.W.M. / Mechanical properties of brain tissue: characterisation and constitutive modelling. Mechanosensitivity of the nervous system. editor / A. Kamkin ; I. Kiseleva. Berlin : Springer, 2009. pp. 249-279 (Mechanosensitivity in Cells and Tissues).
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Dommelen, van, JAW, Hrapko, M & Peters, GWM 2009, Mechanical properties of brain tissue: characterisation and constitutive modelling. in A Kamkin & I Kiseleva (eds), Mechanosensitivity of the nervous system. Mechanosensitivity in Cells and Tissues, vol. 2, Springer, Berlin, pp. 249-279. https://doi.org/10.1007/978-1-4020-8716-5_12

Mechanical properties of brain tissue: characterisation and constitutive modelling. / Dommelen, van, J.A.W.; Hrapko, M.; Peters, G.W.M.

Mechanosensitivity of the nervous system. ed. / A. Kamkin; I. Kiseleva. Berlin : Springer, 2009. p. 249-279 (Mechanosensitivity in Cells and Tissues; Vol. 2).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

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AB - The head is often considered as the most critical region of the human body for life-threatening injuries sustained in accidents. In order to develop effective protective measures, a better understanding of the process of injury development in the brain is required. Finite Element (FE) models are being developed, in order to predict the mechanical response of the contents of the head during impact. To obtain accurate predictions of the mechanical response of the brain, an accurate description of the mechanical behaviour of brain tissue is required. However, up to now no universally accepted data set for the constitutive response of brain tissue exists. The large variation in material properties reported may be caused by differences in testing methods and protocols used. An overview of studies on the mechanical properties of brain tissue is presented, focusing on testing methods. Furthermore, the large strain mechanical response of brain tissue as well as modelling approaches for this behaviour are discussed.

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M3 - Chapter

SN - 978-1-4020-8715-8

T3 - Mechanosensitivity in Cells and Tissues

SP - 249

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BT - Mechanosensitivity of the nervous system

A2 - Kamkin, A.

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Dommelen, van JAW, Hrapko M, Peters GWM. Mechanical properties of brain tissue: characterisation and constitutive modelling. In Kamkin A, Kiseleva I, editors, Mechanosensitivity of the nervous system. Berlin: Springer. 2009. p. 249-279. (Mechanosensitivity in Cells and Tissues). https://doi.org/10.1007/978-1-4020-8716-5_12