Mechanical and histological evaluation of hydroxylapatite cement composites as bone graft substitutes

M. Voor, J.J.C. Arts, S. Klein, L.H.B. Walschot, N. Verdonschot, P. Buma

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

A study, aimed at determining if adding porous particles, tricalcium phosphate/hydroxylapatite or defatted morsellized cancellous allograft bone (MCB), to hydroxylapatite cement (HAC) could improve its incorporation without compromising strength, was presented. Bilateral cancellous bone defects were drilled from the lateral direction in the distal femora of 24 rabbits. Using indentation tests, it was found that both HAC/bone sensitive granules (BSG) and HAC/MCB were stronger than intact cancellous bone initially and after eight weeks in vivo (<0.05). THe HAC groups were also found to be stronger than the empty defects and MCB groups at eight weeks (P<0.05).

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 1 Dec 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Conference

ConferenceTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period17/05/0421/05/04

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Voor, M., Arts, J. J. C., Klein, S., Walschot, L. H. B., Verdonschot, N., & Buma, P. (2004). Mechanical and histological evaluation of hydroxylapatite cement composites as bone graft substitutes. In Transactions - 7th World Biomaterials Congress