Measuring agglutination parameters

W.U. Dittmer (Inventor), P. Kievit, de (Inventor), J.H. Nieuwenhuis (Inventor), M.W.J. Prins (Inventor), L.J. IJzendoorn, van (Inventor), X.J.A. Janssen (Inventor)

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Abstract

A method and system are described for measuring agglutination in a target- induced agglutination assay with one or more magnetic particles performed in a reaction chamber. After the magnetic particles, which are capable of binding to a target are provided in the assay, an agglutination process resulting in agglutinated particles comprising at least one magnetic particle is performed. The method then further comprises applying an a.c. magnetic field (HAC) to the assay and- measuring an effect of the HAC on the one or more magnetic particles unattached to any surface. The measured effect is indicative of one or more agglutination parameters. [on SciFinder (R)]
Original languageEnglish
Patent numberWO2008075285
Publication statusPublished - 26 Jun 2008

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    Dittmer, W. U., Kievit, de, P., Nieuwenhuis, J. H., Prins, M. W. J., IJzendoorn, van, L. J., & Janssen, X. J. A. (2008). Measuring agglutination parameters. (Patent No. WO2008075285).