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Mean aneurysm flow amplitude ratio comparison between DSA and CFD

  • Fred van Nijnatten
  • , Odile Bonnefous
  • , Hernan G. Morales
  • , Thijs Grünhagen
  • , Roel Hermans
  • , Olivier Brina
  • , Vitor Mendes Pereira
  • , Daniel Ruijters

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

The Mean Aneurysm Flow Amplitude ratio (MAFA-ratio) has been proposed to evaluate the efficacy of flow diverting stents during minimally invasive intracranial aneurysm treatment. A method has been described for calculating the MAFA-ratio on high frame-rate digital subtraction angiography (DSA) acquisitions using an optical flow algorithm. In this article we have generated computational fluid dynamics (CFD) simulations using six distinct aneurysms and computed the MAFA-ratios based on these data. Furthermore, the simulations have been used to create virtual angiograms, in order to calculate the MAFA-ratios using the DSA approach. An analysis of the MAFAratios generated by both methods shows that there is a monotone increasing relation between the DSA and CFD based ratios, albeit without a slope being identity. Overall, it can be concluded that the DSA-based ratio is a predictor for the magnitude of aneurysm flow reduction, i.e., for the efficacy of flow diverting stents.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - MICCAI 2015
Subtitle of host publication18th International Conference, Munich, Germany, October 5-9, 2015, Proceedings, Part II
EditorsNassir Navab, Joachim Hornegger, William M. Wells, Alejandro F. Frangi
Place of PublicationCham
PublisherSpringer
Chapter58
Pages485-492
Number of pages8
ISBN (Electronic)978-3-319-24571-3
ISBN (Print)978-3-319-24570-6
DOIs
Publication statusPublished - 2015
Externally publishedYes
Event18th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2015 - Munich, Germany
Duration: 5 Oct 20159 Oct 2015

Publication series

NameLecture Notes in Computer Science (LNCS)
Volume9350
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349
NameImage Processing, Computer Vision, Pattern Recognition, and Graphics (LNIP)
Volume9350

Conference

Conference18th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2015
Country/TerritoryGermany
CityMunich
Period5/10/159/10/15

Keywords

  • Computational fluid dynamics
  • Digital subtraction angiography
  • Flow diversion
  • Mean aneurysm flow amplitude

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