Mathematical models accurately simulate the effect of light on the human circadian rhythm: how can mathematical models of the effects of light on humans help us provide better lighting solutions?

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Abstract

Many biological processes in the body are governed by the circadian pacemaker located in the hypothalamus. We model the effect of light on this human circadian pacemaker based on two interacting processes: the internal clock (circadian rhythm) and the internal sleep drive (sleep homeostat). The biological processes are modeled mathematically using systems of coupled non-linear differential equations. Differences between individuals are expressed by model
parameters. Especially a person’s natural day length (tau) has a great influence on the model’s flow. Mathematical techniques, such as control theory, can be
used to analyze the model. Doing so, we will be able to use them to design smart lighting control systems that automatically adjust the light to achieve certain targets, such as jetlag compensation or mood improvement.
Translated title of the contributionWiskundige modellen simuleren het effect van licht op het menselijke circadiane ritme accuraat
Original languageEnglish
Publication statusPublished - 14 Nov 2017
EventILIAD 2017 - Eindhoven University of Technology, Eindhoven, Netherlands
Duration: 14 Nov 201714 Nov 2017
http://iliad-2017.eventbrite.com/

Conference

ConferenceILIAD 2017
Abbreviated titleILIAD2017
CountryNetherlands
CityEindhoven
Period14/11/1714/11/17
Internet address

Keywords

  • Circadian rhythm
  • Mathematical modeling
  • Light
  • Parameter variation

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  • Prizes

    3rd prize poster contest Iliad 2017

    Bonarius, Jochem H. (Recipient), 14 Nov 2017

    Prize: OtherCareer, activity or publication related prizes (lifetime, best paper, poster etc.)Scientific

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