Abstract
Many biological processes in the body are governed by the circadian pacemaker located in the hypothalamus. We model the effect of light on this human circadian pacemaker based on two interacting processes: the internal clock (circadian rhythm) and the internal sleep drive (sleep homeostat). The biological processes are modeled mathematically using systems of coupled nonlinear differential equations. Differences between individuals are expressed by model
parameters. Especially a person’s natural day length (tau) has a great influence on the model’s flow. Mathematical techniques, such as control theory, can be
used to analyze the model. Doing so, we will be able to use them to design smart lighting control systems that automatically adjust the light to achieve certain targets, such as jetlag compensation or mood improvement.
parameters. Especially a person’s natural day length (tau) has a great influence on the model’s flow. Mathematical techniques, such as control theory, can be
used to analyze the model. Doing so, we will be able to use them to design smart lighting control systems that automatically adjust the light to achieve certain targets, such as jetlag compensation or mood improvement.
Translated title of the contribution  Wiskundige modellen simuleren het effect van licht op het menselijke circadiane ritme accuraat 

Original language  English 
Publication status  Published  14 Nov 2017 
Event  ILIAD 2017  Eindhoven University of Technology, Eindhoven, Netherlands Duration: 14 Nov 2017 → 14 Nov 2017 http://iliad2017.eventbrite.com/ 
Conference
Conference  ILIAD 2017 

Abbreviated title  ILIAD2017 
Country/Territory  Netherlands 
City  Eindhoven 
Period  14/11/17 → 14/11/17 
Internet address 
Keywords
 Circadian rhythm
 Mathematical modeling
 Light
 Parameter variation
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Dive into the research topics of 'Mathematical models accurately simulate the effect of light on the human circadian rhythm: how can mathematical models of the effects of light on humans help us provide better lighting solutions?'. Together they form a unique fingerprint.Prizes

3rd prize poster contest Iliad 2017
Bonarius, Jochem H. (Recipient), 14 Nov 2017
Prize: Other › Career, activity or publication related prizes (lifetime, best paper, poster etc.) › Scientific