Managing trade-offs in protein manufacturing: how much to waste?

T.G. Martagan (Corresponding author), A. Krishnamurthy, P. Leland

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

We consider manufacturing trade-offs for engineer-to-order proteins. The biomanufacturer needs to determine how much protein to produce, and then how much of it to waste in subsequent operations because of the purity and yield trade-offs. We develop a Markov decision model, and determine structural characteristics of the optimal operating policies.
Original languageEnglish
Number of pages16
JournalManufacturing & Service Operations Management
Early online date24 Apr 2019
DOIs
Publication statusE-pub ahead of print - 24 Apr 2019

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Trade-offs
Manufacturing
Protein
Engineers
Decision model

Bibliographical note

065-1445

Cite this

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Managing trade-offs in protein manufacturing: how much to waste? / Martagan, T.G. (Corresponding author); Krishnamurthy, A.; Leland, P.

In: Manufacturing & Service Operations Management, 24.04.2019.

Research output: Contribution to journalArticleAcademicpeer-review

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