Magneto-capillary valve for lab-on-a-chip sample preparation

R.C. Dulk, den; K.A. Schmidt; R. Gill; J.C.B. Jongen; M.W.J. Prins

Magneto-capillary valve for lab-on-a-chip sample preparation

R.C. Dulk, den, K.A. Schmidt, R. Gill, J.C.B. Jongen, M.W.J. Prins

Molecular Biosensing

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

1 Citation (Scopus)

Abstract

We report a novel microtechnology with magneto-capillary valves (MCV), in which magnetic particles are transported through several stationary aqueous liquids by magnetic forces. The technology, which we characterize by studying the balance between magnetic, capillary and friction forces, demonstrates very efficient valving. Purification of DNA in MCV cartridges shows a performance comparable to standard manual purification in tubes. The MCV technology opens new opportunities for integration and miniaturization of automated biological sample preparation.

Original language	English
Title of host publication	Proceedings of 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2010), 3-7 October 2010, Groningen, The Netherlands
Pages	449-451
Publication status	Published - 2010
Event	14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2010 - Groningen, Netherlands Duration: 3 Oct 2010 → 7 Oct 2010 Conference number: 14 http://www.microtasconferences.org/microtas2010/

Conference

Conference	14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2010
Abbreviated title	MicroTAS 2010
Country/Territory	Netherlands
City	Groningen
Period	3/10/10 → 7/10/10
Internet address	http://www.microtasconferences.org/microtas2010/

Cite this

@inproceedings{3b597383fad74ff7b91b16cf20136f3a,

title = "Magneto-capillary valve for lab-on-a-chip sample preparation",

abstract = "We report a novel microtechnology with magneto-capillary valves (MCV), in which magnetic particles are transported through several stationary aqueous liquids by magnetic forces. The technology, which we characterize by studying the balance between magnetic, capillary and friction forces, demonstrates very efficient valving. Purification of DNA in MCV cartridges shows a performance comparable to standard manual purification in tubes. The MCV technology opens new opportunities for integration and miniaturization of automated biological sample preparation.",

author = "{Dulk, den}, R.C. and K.A. Schmidt and R. Gill and J.C.B. Jongen and M.W.J. Prins",

year = "2010",

language = "English",

isbn = "978-0-9798064-3-8",

pages = "449--451",

booktitle = "Proceedings of 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2010), 3-7 October 2010, Groningen, The Netherlands",

note = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2010, MicroTAS 2010 ; Conference date: 03-10-2010 Through 07-10-2010",

url = "http://www.microtasconferences.org/microtas2010/",

}

Dulk, den, RC, Schmidt, KA, Gill, R, Jongen, JCB & Prins, MWJ 2010, Magneto-capillary valve for lab-on-a-chip sample preparation. in Proceedings of 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2010), 3-7 October 2010, Groningen, The Netherlands. pp. 449-451, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2010, Groningen, Netherlands, 3/10/10.

Magneto-capillary valve for lab-on-a-chip sample preparation. / Dulk, den, R.C.; Schmidt, K.A.; Gill, R. et al.
Proceedings of 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2010), 3-7 October 2010, Groningen, The Netherlands. 2010. p. 449-451.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

TY - GEN

T1 - Magneto-capillary valve for lab-on-a-chip sample preparation

AU - Dulk, den, R.C.

AU - Schmidt, K.A.

AU - Gill, R.

AU - Jongen, J.C.B.

AU - Prins, M.W.J.

N1 - Conference code: 14

PY - 2010

Y1 - 2010

N2 - We report a novel microtechnology with magneto-capillary valves (MCV), in which magnetic particles are transported through several stationary aqueous liquids by magnetic forces. The technology, which we characterize by studying the balance between magnetic, capillary and friction forces, demonstrates very efficient valving. Purification of DNA in MCV cartridges shows a performance comparable to standard manual purification in tubes. The MCV technology opens new opportunities for integration and miniaturization of automated biological sample preparation.

AB - We report a novel microtechnology with magneto-capillary valves (MCV), in which magnetic particles are transported through several stationary aqueous liquids by magnetic forces. The technology, which we characterize by studying the balance between magnetic, capillary and friction forces, demonstrates very efficient valving. Purification of DNA in MCV cartridges shows a performance comparable to standard manual purification in tubes. The MCV technology opens new opportunities for integration and miniaturization of automated biological sample preparation.

M3 - Conference contribution

SN - 978-0-9798064-3-8

SP - 449

EP - 451

BT - Proceedings of 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2010), 3-7 October 2010, Groningen, The Netherlands

T2 - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2010

Y2 - 3 October 2010 through 7 October 2010

ER -

Magneto-capillary valve for lab-on-a-chip sample preparation

Abstract

Conference

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