Locally measured microstructural parameters are better associated with vertebral strength than whole bone density

J. Hazrati Marangalou; F. Eckstein; V. Kuhn; K. Ito; M. Cataldi; F. Taddei; B. Rietbergen, van

doi:10.1007/s00198-013-2591-3

Locally measured microstructural parameters are better associated with vertebral strength than whole bone density

J. Hazrati Marangalou, F. Eckstein, V. Kuhn, K. Ito, M. Cataldi, F. Taddei, B. Rietbergen, van

Orthopaedic Biomechanics

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Abstract

Whole vertebrae areal and volumetric bone mineral density (BMD) measurements are not ideal predictors of vertebral fractures. We introduce a technique which enables quantification of bone microstructural parameters at precisely defined anatomical locations. Results show that local assessment of bone volume fraction at the optimal location can substantially improve the prediction of vertebral strength.

Original language	English
Pages (from-to)	1285-1296
Journal	Osteoporosis International
Volume	25
Issue number	4
DOIs	https://doi.org/10.1007/s00198-013-2591-3
Publication status	Published - 2014

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title = "Locally measured microstructural parameters are better associated with vertebral strength than whole bone density",

abstract = "Whole vertebrae areal and volumetric bone mineral density (BMD) measurements are not ideal predictors of vertebral fractures. We introduce a technique which enables quantification of bone microstructural parameters at precisely defined anatomical locations. Results show that local assessment of bone volume fraction at the optimal location can substantially improve the prediction of vertebral strength.",

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AU - Hazrati Marangalou, J.

AU - Eckstein, F.

AU - Kuhn, V.

AU - Ito, K.

AU - Cataldi, M.

AU - Taddei, F.

AU - Rietbergen, van, B.

PY - 2014

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N2 - Whole vertebrae areal and volumetric bone mineral density (BMD) measurements are not ideal predictors of vertebral fractures. We introduce a technique which enables quantification of bone microstructural parameters at precisely defined anatomical locations. Results show that local assessment of bone volume fraction at the optimal location can substantially improve the prediction of vertebral strength.

AB - Whole vertebrae areal and volumetric bone mineral density (BMD) measurements are not ideal predictors of vertebral fractures. We introduce a technique which enables quantification of bone microstructural parameters at precisely defined anatomical locations. Results show that local assessment of bone volume fraction at the optimal location can substantially improve the prediction of vertebral strength.

U2 - 10.1007/s00198-013-2591-3

DO - 10.1007/s00198-013-2591-3

M3 - Article

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SN - 0937-941X

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SP - 1285

EP - 1296

JO - Osteoporosis International

JF - Osteoporosis International

IS - 4

ER -

Locally measured microstructural parameters are better associated with vertebral strength than whole bone density

Abstract

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