Locally measured microstructural parameters are better associated with vertebral strength than whole bone density

J. Hazrati Marangalou, F. Eckstein, V. Kuhn, K. Ito, M. Cataldi, F. Taddei, B. Rietbergen, van

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)
130 Downloads (Pure)

Abstract

Whole vertebrae areal and volumetric bone mineral density (BMD) measurements are not ideal predictors of vertebral fractures. We introduce a technique which enables quantification of bone microstructural parameters at precisely defined anatomical locations. Results show that local assessment of bone volume fraction at the optimal location can substantially improve the prediction of vertebral strength.
Original languageEnglish
Pages (from-to)1285-1296
JournalOsteoporosis International
Volume25
Issue number4
DOIs
Publication statusPublished - 2014

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