Large-scale production of polypropylenimine dendrimers

E.M.M. Brabander, de, A.J. Nijenhuis, E. Murè, J. Keulen, R.W.E.G. Reintjens, F.H.A.M. Vandenbooren, B. Bosman, R. Raat, de, T. Frijns, S.J. Wal, van der, A.M.C.F. Castelijns, J.A. Put, E.W. Meijer

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

47 Citations (Scopus)

Abstract

Th synthesis and characterization of a new series of polypropylenimine (I) dendrimers is reported. Using a repetition of the sequence of a Michael addn. to a primary amine, followed by a heterogeneously catalyzed hydrogenation, ultra-pure polypropylenimine macromols. with mol. wts. £6912 are synthesized. The reaction sequence allows the prepn. of these dendrimers at very large scales, while the availability of a simple purifn. in the sequence affords ultra-pure samples. The I dendrimers are fully characterized; apart from the first 0.5 generation they are all oils, possess a glass transition temp. of -90° to -40°, and are unexpectedly stable. Their intrinsic viscosity drops after generation 4.
Original languageEnglish
Title of host publicationInternational Symposium on New Macromolecular Architectures and Supramolecular Polymers : Denver, Colorado, USA, March 28 - April 2, 1993
EditorsV. Percec, D.A. Tirrell
Place of PublicationBasel
PublisherHüthig & Wepf
Pages51-62
ISBN (Print)3-85739-274-6
DOIs
Publication statusPublished - 1994
Eventconference; International Symposium on New Macromolecular Architectures and Supramolecular Polymers : Denver, Colorado, USA, March 28 - April 2, 1993; 1993-03-28; 1993-04-03 -
Duration: 28 Mar 19933 Apr 1993

Publication series

NameMacromolecular Symposia
Volume77
ISSN (Print)1022-1360

Conference

Conferenceconference; International Symposium on New Macromolecular Architectures and Supramolecular Polymers : Denver, Colorado, USA, March 28 - April 2, 1993; 1993-03-28; 1993-04-03
Period28/03/933/04/93
OtherInternational Symposium on New Macromolecular Architectures and Supramolecular Polymers : Denver, Colorado, USA, March 28 - April 2, 1993

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