Ionic liquids as silica deactivating agents in gas chromatography for direct analysis of primary amines in water

A. Krzyzaniak, W.M.A. Weggemans, B. Schuur, A.B. Haan, de

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    Abstract

    Analysis of primary amines in aqueous samples remains a challenging analytical issue. The preferred approach by gas chromatography is hampered by interactions of free silanol groups with the highly reactive amine groups, resulting in inconsistent measurements. Here, we report a method for direct analysis of aliphatic amines and diamines in aqueous samples by gas chromatography (GC) with silanol deactivation using ionic liquids (ILs). ILs including trihexyl(tetradecyl)phosphonium bis 2,4,4-(trimethylpentyl)phosphinate (Cyphos IL-104), 1-methyl-3-propylimidazolium bis(trifluoromethylsulfonyl)imide [pmim][Tf2N] and N¿-ethyl-N,N,N',N'-tetramethylguanidinium tris(pentafluoroethyl)trifluorophosphate [etmg][FAP] were tested as deactivating media for the GC liner. Solutions of these ILs in methanol were injected in the system prior to the analysis of primary amines. Butane-1,4-diamine (putrescine, BDA) was used as a reference amine. The best results were obtained using the imidazolium IL [pmim][Tf2N]. With this deactivator, excellent reproducibility of the analysis was achieved, and the detection limit of BDA was as low as 1 mM. The applicability of the method was proven for the analysis of two different primary amines (C4–C5) and pentane-1,5-diamine
    Original languageEnglish
    Pages (from-to)9086-9090
    Number of pages5
    JournalJournal of Chromatography, A
    Volume1218
    Issue number50
    DOIs
    Publication statusPublished - 2011

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