Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels

Laura Rijns; Lu Su; Konrad Maxeiner; Giulia Morgese; David Y.W. Ng; Tanja Weil; Patricia Y.W. Dankers

doi:10.1039/d2cc06064g

Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels

Laura Rijns, Lu Su, Konrad Maxeiner, Giulia Morgese, David Y.W. Ng, Tanja Weil, Patricia Y.W. Dankers (Corresponding author)

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

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Abstract

Benzene-1,3,5-tricarboxamide (BTA) glyco-monomers containing one, two or three mannose units are synthesized and formulated into differently patterned supramolecular glycopolymers through homo-assembly or co-assembly with non-functionalized BTAs. Unfortunately, no cellular activity could be detected. Excitingly, these glyco-BTA monomers could be formulated into hydrogels, paving the way for (immune) cell culture.

Original language	English
Pages (from-to)	2090-2093
Number of pages	4
Journal	Chemical Communications, ChemComm
Volume	59
Issue number	15
DOIs	https://doi.org/10.1039/d2cc06064g
Publication status	Published - 16 Feb 2023

Bibliographical note

Publisher Copyright:
© 2023 The Royal Society of Chemistry.

Funding

Funders	Funder number
European Union's Horizon 2020 - Research and Innovation Framework Programme	788618

Keywords

Mannose
Hydrogels

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10.1039/d2cc06064g

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Cite this

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AU - Maxeiner, Konrad

AU - Morgese, Giulia

AU - Ng, David Y.W.

AU - Weil, Tanja

AU - Dankers, Patricia Y.W.

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N2 - Benzene-1,3,5-tricarboxamide (BTA) glyco-monomers containing one, two or three mannose units are synthesized and formulated into differently patterned supramolecular glycopolymers through homo-assembly or co-assembly with non-functionalized BTAs. Unfortunately, no cellular activity could be detected. Excitingly, these glyco-BTA monomers could be formulated into hydrogels, paving the way for (immune) cell culture.

AB - Benzene-1,3,5-tricarboxamide (BTA) glyco-monomers containing one, two or three mannose units are synthesized and formulated into differently patterned supramolecular glycopolymers through homo-assembly or co-assembly with non-functionalized BTAs. Unfortunately, no cellular activity could be detected. Excitingly, these glyco-BTA monomers could be formulated into hydrogels, paving the way for (immune) cell culture.

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Introducing carbohydrate patterning in mannose-decorated supramolecular assemblies and hydrogels

Abstract

Bibliographical note

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Keywords

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