Inter- and intra-observer variation of fetal volume measurements with three-dimensional ultrasound in the first trimester of pregnancy

Nicol A.C. Smeets, Joost van de Ven, S. Guid Oei

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11 Citations (Scopus)
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Abstract

Objectives: To determine the inter- and intra-observer variation of volume calculations of human fetuses at a gestational age of 11 +0-13 +6 weeks by three-dimensional ultrasound (3DUS). Methods: 3DUS datasets were acquired during nuchal translucency measurements. The fetal volume (FV) was measured in 65 cases by two independent investigators. The Virtual Organ Computer aided AnaLysis (VOCAL™) imaging software was used to manually calculate the FV (rotational angle 9°). Inter- and intra-observer variation were assessed by Bland-Altman plots and intraclass correlation coefficients (ICC). Results: Both inter- and intraobserver reproducibility were highly reliable as shown by the Bland-Altman plots and an ICC of respectively 0.934 and 0.994. Conclusion: FV calculation by 3DUS with VOCAL and a rotational angle of 9° is feasible and has a high inter- and intraobserver reliability in the first trimester of pregnancy.

Original languageEnglish
Pages (from-to)539-543
Number of pages5
JournalJournal of Perinatal Medicine
Volume39
Issue number5
DOIs
Publication statusPublished - 1 Sep 2011

Keywords

  • Fetal volume
  • first trimester
  • interobserver variation
  • intraobserver variation
  • three-dimensional ultrasound

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