Integrating a 1.5 T MRI scanner with a 6 MV accelerator: proof of concept

B.W. Raaymakers, J.J.W. Lagendijk, J.A. Overweg, J.G.M. Kok, A.J.E. Raaijmakers, E.M. Kerkhof, R.W. van der Put, I. Meijsing, S.P.M. Crijns, F. Benedosso, M. van Vulpen, C.H.W. de Graaff, J.J.B. Allen, K.J. Brown

Research output: Contribution to journalArticleAcademicpeer-review

495 Citations (Scopus)


At the UMC Utrecht, The Netherlands, we have constructed a prototype MRI accelerator. The prototype is a modified 6 MV Elekta (Crawley, UK) accelerator next to a modified 1.5 T Philips Achieva (Best, The Netherlands) MRI system. From the initial design onwards, modifications to both systems were aimed to yield simultaneous and unhampered operation of the MRI and the accelerator. Indeed, the simultaneous operation is shown by performing diagnostic quality 1.5 T MRI with the radiation beam on. No degradation of the performance of either system was found. The integrated 1.5 T MRI system and radiotherapy accelerator allow simultaneous irradiation and MR imaging. The full diagnostic imaging capacities of the MRI can be used; dedicated sequences for MRI-guided radiotherapy treatments will be developed. This proof of concept opens the door towards a clinical prototype to start testing MRI-guided radiation therapy (MRIgRT) in the clinic.

Original languageEnglish
Pages (from-to)N229-N237
JournalPhysics in Medicine and Biology
Issue number12
Publication statusPublished - 21 Jun 2009
Externally publishedYes


  • Equipment Design
  • Equipment Failure Analysis
  • Magnetic Resonance Imaging
  • Particle Accelerators
  • Pilot Projects
  • Radiotherapy, Computer-Assisted
  • Systems Integration
  • Evaluation Studies
  • Journal Article
  • Research Support, Non-U.S. Gov't


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