Influence of strain and contact guidance on collagen organization in engineered cardiovascular tissues : implications for in situ tissue engineering

N. de Jonge; G. Argento; F.P.T. Baaijens; C.V.C. Bouten

doi:10.1115/SBC2013-14242

Influence of strain and contact guidance on collagen organization in engineered cardiovascular tissues : implications for in situ tissue engineering

N. de Jonge, G. Argento, F.P.T. Baaijens, C.V.C. Bouten

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Abstract

Cardiovascular tissues have a prominent load-bearing function. Collagen fibers in the extracellular matrix provide strength to these tissues. In particular the content and organization of these fibers contribute to overall strength [1]. In case of changes in mechanical demand, collagen content and organization can be adapted; a process referred to as collagen remodeling. For the creation of engineered cardiovascular tissues knowledge about collagen remodeling is of utmost importance to produce tissues with load bearing function. In case of in situ tissue engineering (TE) collagen content and organization in the developing tissue can be influenced by local tissue strains as well as scaffold structure and degradation properties [2, 3].

Original language	English
Title of host publication	ASME 2013 Summer Bioengineering Conference, SBC 2013
Publisher	American Society of Mechanical Engineers
Pages	1-2
Volume	1 B
ISBN (Print)	978-0-7918-5561-4
DOIs	https://doi.org/10.1115/SBC2013-14242
Publication status	Published - 2013
Event	ASME 2013 Summer Bioengineering Conference SBC 2013 - Sunriver, United States Duration: 26 Jun 2013 → 29 Jun 2013 http://www.asmeconferences.org/SBC2013/

Conference

Conference	ASME 2013 Summer Bioengineering Conference SBC 2013
Abbreviated title	SBC 2013
Country/Territory	United States
City	Sunriver
Period	26/06/13 → 29/06/13
Internet address	http://www.asmeconferences.org/SBC2013/

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de Jonge, N., Argento, G., Baaijens, F. P. T., & Bouten, C. V. C. (2013). Influence of strain and contact guidance on collagen organization in engineered cardiovascular tissues : implications for in situ tissue engineering. In ASME 2013 Summer Bioengineering Conference, SBC 2013 (Vol. 1 B, pp. 1-2). Article SBC2013-14242 American Society of Mechanical Engineers. https://doi.org/10.1115/SBC2013-14242

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title = "Influence of strain and contact guidance on collagen organization in engineered cardiovascular tissues : implications for in situ tissue engineering",

abstract = "Cardiovascular tissues have a prominent load-bearing function. Collagen fibers in the extracellular matrix provide strength to these tissues. In particular the content and organization of these fibers contribute to overall strength [1]. In case of changes in mechanical demand, collagen content and organization can be adapted; a process referred to as collagen remodeling. For the creation of engineered cardiovascular tissues knowledge about collagen remodeling is of utmost importance to produce tissues with load bearing function. In case of in situ tissue engineering (TE) collagen content and organization in the developing tissue can be influenced by local tissue strains as well as scaffold structure and degradation properties [2, 3].",

author = "{de Jonge}, N. and G. Argento and F.P.T. Baaijens and C.V.C. Bouten",

year = "2013",

doi = "10.1115/SBC2013-14242",

language = "English",

isbn = "978-0-7918-5561-4",

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booktitle = "ASME 2013 Summer Bioengineering Conference, SBC 2013",

publisher = "American Society of Mechanical Engineers",

address = "United States",

note = "ASME 2013 Summer Bioengineering Conference SBC 2013, SBC 2013 ; Conference date: 26-06-2013 Through 29-06-2013",

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}

de Jonge, N, Argento, G, Baaijens, FPT & Bouten, CVC 2013, Influence of strain and contact guidance on collagen organization in engineered cardiovascular tissues : implications for in situ tissue engineering. in ASME 2013 Summer Bioengineering Conference, SBC 2013. vol. 1 B, SBC2013-14242, American Society of Mechanical Engineers, pp. 1-2, ASME 2013 Summer Bioengineering Conference SBC 2013, Sunriver, Oregon, United States, 26/06/13. https://doi.org/10.1115/SBC2013-14242

Influence of strain and contact guidance on collagen organization in engineered cardiovascular tissues : implications for in situ tissue engineering. / de Jonge, N.; Argento, G.; Baaijens, F.P.T. et al.
ASME 2013 Summer Bioengineering Conference, SBC 2013. Vol. 1 B American Society of Mechanical Engineers, 2013. p. 1-2 SBC2013-14242.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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N2 - Cardiovascular tissues have a prominent load-bearing function. Collagen fibers in the extracellular matrix provide strength to these tissues. In particular the content and organization of these fibers contribute to overall strength [1]. In case of changes in mechanical demand, collagen content and organization can be adapted; a process referred to as collagen remodeling. For the creation of engineered cardiovascular tissues knowledge about collagen remodeling is of utmost importance to produce tissues with load bearing function. In case of in situ tissue engineering (TE) collagen content and organization in the developing tissue can be influenced by local tissue strains as well as scaffold structure and degradation properties [2, 3].

AB - Cardiovascular tissues have a prominent load-bearing function. Collagen fibers in the extracellular matrix provide strength to these tissues. In particular the content and organization of these fibers contribute to overall strength [1]. In case of changes in mechanical demand, collagen content and organization can be adapted; a process referred to as collagen remodeling. For the creation of engineered cardiovascular tissues knowledge about collagen remodeling is of utmost importance to produce tissues with load bearing function. In case of in situ tissue engineering (TE) collagen content and organization in the developing tissue can be influenced by local tissue strains as well as scaffold structure and degradation properties [2, 3].

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VL - 1 B

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T2 - ASME 2013 Summer Bioengineering Conference SBC 2013

Y2 - 26 June 2013 through 29 June 2013

ER -

Influence of strain and contact guidance on collagen organization in engineered cardiovascular tissues : implications for in situ tissue engineering

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