@inproceedings{7ca6e66a01aa43a5972a58621b9e2325,
title = "Influence of steady fluid flow on solute transfer in a two-dimensional carotid artery bifurcation",
abstract = "The aim of this project is to find an answer to the question if solute transfer to different parts of the blood vessel wall is different due to flow conditions. If so, this might help to explain the predelection of atherogenesis to occur first at certain parts of the arterial wall. In this report two cases are evaluated: solute transfer in the common carotid artery on the basis of an analytical approximation and solute transfer in the carotid artery bifurcation on the basis of a numerical approximation using a finite element method. In both cases two-dimensional, steady flow through a rigid geometry is studied. As model solutes are used: EDTA (low molecular solute) and albumin (high molecular solute). In a first approach all solute transfer within the vessel wall is described by a diffusion type model. For high molecular solutes this model is only valid when the difference between blood and tissue solute concentrations is large. It is concluded that neither in the common carotid artery nor in the carotid artery bifurcation blood flow has a significant influence on mass transfer to the vessel wall. In both situations the vessel wall is dominating the overall mass transfer. [Author abstract; 6 Refs; In English]",
author = "M.I.M. Stoop and P.H.M. Bovendeerd",
year = "1991",
language = "English",
isbn = "0-7918-0889-0",
series = "BED",
publisher = "American Society of Mechanical Engineers",
pages = "223--226",
booktitle = "1991 Advances in bioengineering : presented at the winter annual meeting of the American Society of Mechanical Engineers, Atlanta, Georgia, December 1-6, 1991 / Ed. R. Vanderby Jr",
address = "United States",
}